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Adrenaline (Epinephrine)

 𝐀𝐝𝐫𝐞𝐧𝐚𝐥𝐢𝐧𝐞 (𝐄𝐩𝐢𝐧𝐞𝐩𝐡𝐫𝐢𝐧𝐞):  𝐈𝐧𝐝𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬: 1. Anaphylaxis:  Adrenaline is the 𝐟𝐢𝐫𝐬𝐭-𝐥𝐢𝐧𝐞 𝐭𝐫𝐞𝐚𝐭𝐦𝐞𝐧𝐭 for anaphylaxis, a severe allergic reaction that can cause difficulty breathing, low blood pressure, and shock.  2. Cardiac Arrest:  Adrenaline is used in advanced cardiac life support (ACLS) protocols to restore normal heart rhythm in patients with cardiac arrest.  3. Asthma:  Adrenaline can be used in the treatment of severe asthma attacks that are unresponsive to other bronchodilators.  4. Severe Allergic Reactions:  Adrenaline can be used to treat severe allergic reactions to medications, insect stings, or food. 𝐌𝐞𝐜𝐡𝐚𝐧𝐢𝐬𝐦 𝐨𝐟 𝐀𝐜𝐭𝐢𝐨𝐧 𝐨𝐟 𝐀𝐝𝐫𝐞𝐧𝐚𝐥𝐢𝐧𝐞:  Adrenaline acts on various adrenergic receptors in the body.  It stimulates 𝐛𝐨𝐭𝐡 𝐚𝐥𝐩𝐡𝐚 𝐚𝐧𝐝 𝐛𝐞𝐭𝐚 adrenergic receptors, leading to several physiological effects.  Adrenaline causes vasoconstriction, which increases blood pressure and helps to reverse t

Sugar and Metabolic disease

1. Sugary drinks provide empty calories and no nutritional value.  Avoiding them for a week can help reduce calorie intake and support a healthier diet.  2. Frequent consumption of sugary drinks is associated with an increased risk of developing type 2 diabetes.  The large amounts of rapidly absorbed sugars lead to prolonged elevated blood glucose and insulin levels, which can worsen insulin resistance over time. 3. The sugars in sugary drinks interact with oral bacteria to produce acids that erode tooth enamel.  This erosion makes teeth more susceptible to cavities and dental decay. 4. Sugary drinks have been linked to higher blood pressure.  The sugars may increase blood glucose and insulin levels, which can alter blood vessel function and lead to hypertension.  The excess calories may also contribute to weight gain, another risk factor for high blood pressure. 5. The association between sugary drinks and increased heart disease risk is likely mediated by their effects on diabetes, o

Wilson's disease

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 Wilson's disease Etiology:  Wilson's disease is an autosomal recessive disorder caused by mutations in the ATP7B gene, leading to impaired hepatic copper transport and subsequent copper accumulation in various tissues. Pathogenesis:  In Wilson's disease, the impaired copper transport results in copper deposition in the liver, brain, cornea, and other organs.  The exact mechanism of cardiomyopathy in Wilson's disease is not fully understood, but it is believed to be related to the toxic effects of copper accumulation in cardiac tissues. Clinical Features:  In addition to the Kayser-Fleischer ring (a brownish-green ring around the cornea), Wilson's disease can present with  - hepatic symptoms (such as hepatomegaly, jaundice, and liver dysfunction) - neurological symptoms (such as tremors, dystonia, and dysarthria) - psychiatric symptoms (such as personality changes and depression).  - Cardiac manifestations, including cardiomyopathy, arrhythmi

Impetigo

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Impetigo is a common and contagious skin infection caused by bacteria, typically Streptococcus pyogenes - Group A or Staphylococcus aureus. It is most commonly seen in children,  2 through 5 years old.  but it can affect individuals of all ages.  Impetigo is more common in areas with hot, humid summers and mild winters (subtropics), or wet and dry seasons (tropics), but it can occur anywhere. Proper management of impetigo involves both hygiene and medical treatment. Here are the steps to manage impetigo: Maintain Good Hygiene: Cleanliness is essential. Encourage the infected individual to wash their hands frequently, avoid touching the impetigo sores, and use separate towels and personal items to prevent the spread of the infection. Trim fingernails to reduce the risk of scratching and spreading the infection. Topical Antibiotics: Most cases of impetigo can be managed with topical antibiotics. These are typically available in the form of creams or ointments, and they should be applied

Greenstick Fracture of Clavicle

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  A greenstick fracture of the clavicle, or collarbone, is a relatively common injury in children. The management of this type of fracture typically involves the following steps: Initial Assessment: As with any injury, begin by assessing the child's condition to ensure there are no other injuries or complications. Examine for any signs of neurovascular compromise, such as loss of sensation or circulation, and assess for any open wounds. Immobilization: The primary goal in managing a greenstick fracture of the clavicle is to immobilize the fracture to allow for proper healing. This is often achieved with a figure-eight or sling immobilizer, which helps to support the shoulder and keep the clavicle in the correct position. The figure-eight splint or brace should be applied in a way that prevents excessive movement of the clavicle. Pain Management: Provide pain relief for the child as needed. Over-the-counter pain relievers like acetaminophen or ibuprofen can be used under the guidanc

Greenstick fractures

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 Greenstick fractures are common in children due to their developing and more flexible bones. These fractures are typically incomplete, where the bone cracks but doesn't break all the way through. The most common site for greenstick fractures is in the forearm, particularly the radius, but they can occur in other long bones as well. Here's how greenstick fractures in children are typically managed: GreenStick Fracture of Left Clavicle Initial Assessment: As with any fracture, the first step is to assess the child's condition and ensure there are no other injuries. You should check for any signs of neurovascular compromise (loss of sensation or circulation), and assess for any open wounds. Immobilization: The main goal in managing greenstick fractures is to stabilize the fracture to promote healing. This is usually done with a cast. The injured limb is typically immobilized in a cast or splint. For greenstick fractures of the forearm, both the radius and ulna are often immob

Flexural eczema

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Flexural eczema, also known as atopic dermatitis or atopic eczema, is a common skin condition characterized by inflammation and itchiness of the skin, particularly in the skin folds or flexural areas. These areas include the folds of the elbows, knees, wrists, neck, and sometimes the face. It is a chronic condition and often appears in childhood, though it can affect people of all ages. The exact cause of flexural eczema is not fully understood, but it is believed to involve a combination of genetic, environmental, and immune system factors. Common symptoms and features of flexural eczema include: Red, inflamed skin: The affected areas become red, and swollen, and may ooze or crust over due to scratching. Intense itching: Itchiness is a hallmark symptom of eczema and can be severe, leading to further skin damage when scratched. Dry, scaly skin: The skin may become dry, flaky, and rough in texture. Recurrence: Eczema often has a relapsing and remitting course, meaning it can flare up a