Adrenaline (Epinephrine)
đđđĢđđ§đđĨđĸđ§đ (đđŠđĸđ§đđŠđĄđĢđĸđ§đ):
đđ§đđĸđđđđĸđ¨đ§đŦ:
1. Anaphylaxis:
Adrenaline is the đđĸđĢđŦđ-đĨđĸđ§đ đđĢđđđđĻđđ§đ for anaphylaxis, a severe allergic reaction that can cause difficulty breathing, low blood pressure, and shock.
2. Cardiac Arrest:
Adrenaline is used in advanced cardiac life support (ACLS) protocols to restore normal heart rhythm in patients with cardiac arrest.
3. Asthma:
Adrenaline can be used in the treatment of severe asthma attacks that are unresponsive to other bronchodilators.
4. Severe Allergic Reactions:
Adrenaline can be used to treat severe allergic reactions to medications, insect stings, or food.
đđđđĄđđ§đĸđŦđĻ đ¨đ đđđđĸđ¨đ§ đ¨đ đđđĢđđ§đđĨđĸđ§đ:
Adrenaline acts on various adrenergic receptors in the body.
It stimulates đđ¨đđĄ đđĨđŠđĄđ đđ§đ đđđđ adrenergic receptors, leading to several physiological effects.
Adrenaline causes vasoconstriction, which increases blood pressure and helps to reverse the low blood pressure seen in anaphylaxis.
It also relaxes the smooth muscles of the airways, improving breathing.
Additionally, adrenaline increases the heart rate and cardiac output, which can be beneficial in cardiac arrest.
đđ¨đŦđđ đ đđ§đ đđĸđĨđŽđđĸđ¨đ§:
The dosage and dilution of adrenaline vary depending on the indication and the route of administration.
Here are some commonly used dosages:
1. Anaphylaxis: Intramuscular injection of đ.đ-đ.đ đĻđ (đ:đđđđ đđ¨đ§đđđ§đđĢđđđĸđ¨đ§) into the lateral thigh.
2. Cardiac Arrest: Intravenous bolus of đ đĻđ (đ:đđ,đđđ đđ¨đ§đđđ§đđĢđđđĸđ¨đ§) every đ-đ minutes during resuscitation.
3. Asthma: Nebulized solution of đ đĻđ (đ:đđđđ đđ¨đ§đđđ§đđĢđđđĸđ¨đ§) diluted in đ-đ đĻđ of đ§đ¨đĢđĻđđĨ đŦđđĨđĸđ§đ.
đđđ¯đđĢđŦđ đđđđđđđŦ:
Although adrenaline is generally safe when used appropriately, it can have some adverse effects, including:
1. Increased heart rate and palpitations
2. Elevated blood pressure
3. Headache and dizziness
4. Tremor and anxiety
5. Nausea and vomiting
đđĄđ˛ đĸđŦ đđŠđĸđ§đđŠđĄđĢđĸđ§đ đŠđĢđđđđĢđĢđđ đ¨đ¯đđĢ đđ đĸđ§ đđ§đđŠđĄđ˛đĨđđąđĸđŦ?
đđŠđĸđ§đđŠđĄđĢđĸđ§đ (đđđĢđđ§đđĨđĸđ§đ) is preferred over đ§đ¨đĢđđŠđĸđ§đđŠđĄđĢđĸđ§đ (đđ) in the treatment of anaphylaxis due to its broader range of actions.
Epinephrine stimulates đđ¨đđĄ đđĨđŠđĄđ đđ§đ đđđđ adrenergic receptors, leading to đ¯đđŦđ¨đđ¨đ§đŦđđĢđĸđđđĸđ¨đ§, đđĢđ¨đ§đđĄđ¨đđĸđĨđđđĸđ¨đ§, & đĸđ§đđĢđđđŦđđ đđđĢđđĸđđ đ¨đŽđđŠđŽđ.
This combination of effects helps to đĢđđ¯đđĢđŦđ the đĨđ¨đ° đđĨđ¨đ¨đ đŠđĢđđŦđŦđŽđĢđ, đĸđĻđŠđĢđ¨đ¯đ đđĢđđđđĄđĸđ§đ , & đĢđđŦđđ¨đĢđ đđĸđĢđđŽđĨđđđĸđ¨đ§ in anaphylaxis.
đđ¨đĢđđŠđĸđ§đđŠđĄđĢđĸđ§đ, on the other hand, đŠđĢđĸđĻđđĢđĸđĨđ˛ acts on đđĨđŠđĄđ adrenergic receptors and has a more đĨđĸđĻđĸđđđ effect on đđĢđ¨đ§đđĄđ¨đđĸđĨđđđĸđ¨đ§ and đđđĢđđĸđđ đ¨đŽđđŠđŽđ.
đđŠđĸđ§đđŠđĄđĢđĸđ§đ'đŦ ability to stimulate đđđđ adrenergic receptors makes it a đĻđ¨đĢđ đđđđđđđĸđ¯đ treatment for đđ§đđŠđĄđ˛đĨđđąđĸđŦ, as it addresses đđ¨đđĄ the đđđĢđđĸđ¨đ¯đđŦđđŽđĨđđĢ and đĢđđŦđŠđĸđĢđđđ¨đĢđ˛ symptoms of the condition.
đđ, which primarily acts on đđĨđŠđĄđ adrenergic receptors, is đĻđ¨đĢđ đđ¨đĻđĻđ¨đ§đĨđ˛ used in the treatment of đŦđđŠđđĸđ đŦđĄđ¨đđ¤ or other forms of distributive shock where đ¯đđŦđ¨đđ¨đ§đŦđđĢđĸđđđĸđ¨đ§ is the primary goal.
Comments
Post a Comment